Ancestry-dependent gene expression correlates with reprogramming to pluripotency and multiple dynamic biological processes

Induced pluripotent stem cells (iPSCs) can be derived from differentiated cells, enabling the generation of personalized disease models by differentiating patient-derived iPSCs into disease-relevant cell lines. While genetic variability between different iPSC lines affects differentiation potential,...

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Vydáno v:Sci Adv
Hlavní autoři: Bisogno, Laura S., Yang, Jun, Bennett, Brian D., Ward, James M., Mackey, Lantz C., Annab, Lois A., Bushel, Pierre R., Singhal, Sandeep, Schurman, Shepherd H., Byun, Jung S., Nápoles, Anna María, Pérez-Stable, Eliseo J., Fargo, David C., Gardner, Kevin, Archer, Trevor K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679169/
https://ncbi.nlm.nih.gov/pubmed/33219026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc3851
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