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Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell Reprogramming
Reprogramming to pluripotency involves drastic restructuring of both metabolism and the epigenome. However, induced pluripotent stem cells (iPSC) retain transcriptional memory, epigenetic memory, and metabolic memory from their somatic cells of origin and acquire aberrant characteristics distinct fr...
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| Publié dans: | Stem Cells Int |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Hindawi
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6525803/ https://ncbi.nlm.nih.gov/pubmed/31191682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7360121 |
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