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Oxygen Regulates Human Pluripotent Stem Cell Metabolic Flux

Metabolism has been shown to alter cell fate in human pluripotent stem cells (hPSC). However, current understanding is almost exclusively based on work performed at 20% oxygen (air), with very few studies reporting on hPSC at physiological oxygen (5%). In this study, we integrated metabolic, transcr...

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Détails bibliographiques
Publié dans:Stem Cells Int
Auteurs principaux: Lees, Jarmon G., Cliff, Timothy S., Gammilonghi, Amanda, Ryall, James G., Dalton, Stephen, Gardner, David K., Harvey, Alexandra J.
Format: Artigo
Langue:Inglês
Publié: Hindawi 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545818/
https://ncbi.nlm.nih.gov/pubmed/31236115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8195614
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