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MYC CONTROLS HUMAN PLURIPOTENT STEM CELL FATE DECISIONS THROUGH REGULATION OF METABOLIC FLUX
As human pluripotent stem cells (hPSCs) exit pluripotency they are thought to switch from a glycolytic mode of energy generation to one more dependent on oxidative phosphorylation. Here we show that although metabolic switching occurs during early mesoderm and endoderm differentiation, high glycolyt...
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| Pubblicato in: | Cell Stem Cell |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5644510/ https://ncbi.nlm.nih.gov/pubmed/28965765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.08.018 |
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