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Myc represses primitive endoderm differentiation in pluripotent stem cells

The generation of induced pluripotent stem cells (iPSCs) provides a novel method to facilitate investigations into the mechanisms that control stem cell pluripotency and self-renewal. Myc has previously been shown to be critical for murine embryonic stem cell (mESC) maintenance, while also enhancing...

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Hlavní autoři: Smith, Keriayn N., Singh, Amar M., Dalton, Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954754/
https://ncbi.nlm.nih.gov/pubmed/20804970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.06.023
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