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Reconciling the different roles of Gsk3β in “naïve” and “primed” pluripotent stem cells

Signaling pathways orchestrated by PI3K/Akt, Raf/Mek/Erk and Wnt/β-catenin are known to play key roles in the self-renewal and differentiation of pluripotent stem cells. The serine/threonine protein kinase Gsk3β has roles in all three pathways, making its exact function difficult to decipher. Conseq...

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Detalhes bibliográficos
Main Authors: Singh, Amar M., Bechard, Matthew, Smith, Keriayn, Dalton, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442909/
https://ncbi.nlm.nih.gov/pubmed/22825252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21110
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