Ancestry-dependent gene expression correlates with reprogramming to pluripotency and multiple dynamic biological processes

Induced pluripotent stem cells (iPSCs) can be derived from differentiated cells, enabling the generation of personalized disease models by differentiating patient-derived iPSCs into disease-relevant cell lines. While genetic variability between different iPSC lines affects differentiation potential,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Bisogno, Laura S., Yang, Jun, Bennett, Brian D., Ward, James M., Mackey, Lantz C., Annab, Lois A., Bushel, Pierre R., Singhal, Sandeep, Schurman, Shepherd H., Byun, Jung S., Nápoles, Anna María, Pérez-Stable, Eliseo J., Fargo, David C., Gardner, Kevin, Archer, Trevor K.
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2020
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679169/
https://ncbi.nlm.nih.gov/pubmed/33219026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc3851
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