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Drosophila hedgehog can act as a morphogen in the absence of regulated Ci processing
Extracellular Hedgehog (Hh) proteins induce transcriptional changes in target cells by inhibiting the proteolytic processing of full-length Drosophila Ci or mammalian Gli proteins to nuclear transcriptional repressors and by activating the full-length Ci or Gli proteins. We used Ci variants expresse...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7679133/ https://ncbi.nlm.nih.gov/pubmed/33084577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61083 |
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