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Drosophila hedgehog can act as a morphogen in the absence of regulated Ci processing

Extracellular Hedgehog (Hh) proteins induce transcriptional changes in target cells by inhibiting the proteolytic processing of full-length Drosophila Ci or mammalian Gli proteins to nuclear transcriptional repressors and by activating the full-length Ci or Gli proteins. We used Ci variants expresse...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Little, Jamie C, Garcia-Garcia, Elisa, Sul, Amanda, Kalderon, Daniel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679133/
https://ncbi.nlm.nih.gov/pubmed/33084577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61083
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