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Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia

Hedgehog (Hh) signalling is important in development, stem cell biology and disease. In a variety of tissues, Hh acts as a morphogen to regulate growth and cell fate specification. Several hypotheses have been proposed to explain morphogen movement, one of which is transport via filopodia-like protr...

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Detalhes bibliográficos
Main Authors: Bischoff, Marcus, Gradilla, Ana-Citlali, Seijo, Irene, Andrés, Germán, Rodríguez-Navas, Carmen, González-Méndez, Laura, Guerrero, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840581/
https://ncbi.nlm.nih.gov/pubmed/24121526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2856
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