Integration of single-cell datasets reveals novel transcriptomic signatures of β-cells in human type 2 diabetes

Pancreatic islet β-cell failure is key to the onset and progression of type 2 diabetes (T2D). The advent of single-cell RNA sequencing (scRNA-seq) has opened the possibility to determine transcriptional signatures specifically relevant for T2D at the β-cell level. Yet, applications of this technique...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:NAR Genom Bioinform
Main Authors: Bosi, Emanuele, Marselli, Lorella, De Luca, Carmela, Suleiman, Mara, Tesi, Marta, Ibberson, Mark, Eizirik, Decio L, Cnop, Miriam, Marchetti, Piero
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Standard Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679065/
https://ncbi.nlm.nih.gov/pubmed/33575641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqaa097
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki