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TARGETING TELOMERASE FOR CANCER THERAPY

Telomere maintenance via telomerase reactivation is a nearly universal hallmark of cancer cells which enables replicative immortality. In contrast, telomerase activity is silenced in most adult somatic cells. Thus, telomerase represents an attractive target for highly selective cancer therapeutics....

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Detalles Bibliográficos
Publicado en:Oncogene
Main Authors: Guterres, Adam N, Villanueva, Jessie
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678952/
https://ncbi.nlm.nih.gov/pubmed/32733068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01405-w
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