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Beyond Telomerase: Telomere Instability as a Novel Target for Cancer Therapy
Telomeres are areas of heterochromatin composed of TTAGGG repeats located at the ends of linear chromosomes. They play a critical role in keeping genome stable and preventing premature aging diseases and the development of cancer. Characterizing mechanisms of telomere maintenance and understanding h...
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| Publicado no: | J Mol Genet Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4844356/ https://ncbi.nlm.nih.gov/pubmed/27123041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/1747-0862.1000091 |
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