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LRRK2 and the Endolysosomal System in Parkinson’s Disease
Mutations in leucine-rich repeat kinase 2 (LRRK2) cause autosomal dominant familial Parkinson’s disease (PD), with pathogenic mutations enhancing LRRK2 kinase activity. There is a growing body of evidence indicating that LRRK2 contributes to neuronal damage and pathology both in familial and sporadi...
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| Pubblicato in: | J Parkinsons Dis |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
IOS Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7677880/ https://ncbi.nlm.nih.gov/pubmed/33044192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-202138 |
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