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Targeting the PD-1/PD-L1 Axis in Human Vitiligo
Autoreactive CD8(+) T cells play a pivotal role in melanocyte destruction in autoimmune vitiligo. Immunotherapy for melanoma often leads to autoimmune side-effects, among which vitiligo-like depigmentation, indicating that targeting immune checkpoints can break peripheral tolerance against self-anti...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7677560/ https://ncbi.nlm.nih.gov/pubmed/33240267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.579022 |
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