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Effects of Nucleotide and End-Dependent Actin Conformations on Polymerization

The regulation of actin is key for controlled cellular function. Filaments are regulated by actin-binding proteins, but the nucleotide state of actin is also an important factor. From extended molecular dynamics simulations, we find that both nucleotide states of the actin monomer have significantly...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Jepsen, Lauren, Sept, David
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677244/
https://ncbi.nlm.nih.gov/pubmed/33080221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.09.024
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