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Guanosine Tetraphosphate Has a Similar Affinity for Each of Its Two Binding Sites on Escherichia coli RNA Polymerase

During nutrient deprivation, the bacterial cell undergoes a stress response known as the stringent response. This response is characterized by induction of the nucleotide derivative guanosine tetraphosphate (ppGpp) that dramatically modulates the cell’s transcriptome. In Escherichia coli, ppGpp regu...

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Détails bibliographiques
Publié dans:Front Microbiol
Auteurs principaux: Myers, Angela R., Thistle, Danielle P., Ross, Wilma, Gourse, Richard L.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7676912/
https://ncbi.nlm.nih.gov/pubmed/33250875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.587098
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