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Guanosine Tetraphosphate Has a Similar Affinity for Each of Its Two Binding Sites on Escherichia coli RNA Polymerase

During nutrient deprivation, the bacterial cell undergoes a stress response known as the stringent response. This response is characterized by induction of the nucleotide derivative guanosine tetraphosphate (ppGpp) that dramatically modulates the cell’s transcriptome. In Escherichia coli, ppGpp regu...

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Pubblicato in:Front Microbiol
Autori principali: Myers, Angela R., Thistle, Danielle P., Ross, Wilma, Gourse, Richard L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7676912/
https://ncbi.nlm.nih.gov/pubmed/33250875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.587098
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