Process Development for 6-Aminopenicillanic Acid Production Using Lentikats-Encapsulated Escherichia coli Cells Expressing Penicillin V Acylase

[Image: see text] Penicillin V acylase (PVA, EC 3.5.1.11) hydrolyzes the side chain of phenoxymethylpenicillin (Pen V) and finds application in the manufacture of the pharmaceutical intermediate 6-aminopenicillanic acid (6-APA). Here, we report the scale-up of cultivation of Escherichia coli whole c...

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Bibliografski detalji
Izdano u:ACS Omega
Glavni autori: Sawant, Amol M., Sunder, Avinash Vellore, Vamkudoth, Koteswara Rao, Ramasamy, Sureshkumar, Pundle, Archana
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2020
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7675567/
https://ncbi.nlm.nih.gov/pubmed/33225127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c02813
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