Adiponectin Inhibits NLRP3 Inflammasome Activation in Nonalcoholic Steatohepatitis via AMPK-JNK/ErK1/2-NFκB/ROS Signaling Pathways

Adiponectin, an adipose-derived adipokine, possesses a hepatoprotective role in various liver disorders. It has been reported that hypoadiponectinemia can affect with the progression of non-alcoholic fatty liver diseases (NAFLD). Inflammasome activation has been recognized to play a major role durin...

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Bibliografiske detaljer
Udgivet i:Front Med (Lausanne)
Main Authors: Dong, Zhixia, Zhuang, Qian, Ye, Xin, Ning, Min, Wu, Shan, Lu, Lungen, Wan, Xinjian
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674946/
https://ncbi.nlm.nih.gov/pubmed/33251225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2020.546445
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