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Palmitic acid stimulates NLRP3 inflammasome activation through TLR4-NF-κB signal pathway in hepatic stellate cells

BACKGROUND: The NLRP3 inflammasome activation plays an important role in the development of NASH and fibrogenesis. However, the mechanisms involved in NLRP3 activation in hepatic stellate cells (HSCs) have been unclear. The aim of this study was to investigate the mechanism of NLRP3 activation in HS...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Ann Transl Med
Egile Nagusiak: Dong, Zhixia, Zhuang, Qian, Ning, Min, Wu, Shan, Lu, Lungen, Wan, Xinjian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: AME Publishing Company 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7154441/
https://ncbi.nlm.nih.gov/pubmed/32309315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2020.02.21
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