Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay

Excessive ethanol exposure can cause mitochondrial and cellular toxicity. In order to discover potential counteracting interventions, it is essential to develop assays capable of capturing the consequences of ethanol exposure in human neurons, and particularly dopaminergic neurons that are crucial f...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Zink, Annika, Conrad, Josefin, Telugu, Narasimha Swami, Diecke, Sebastian, Heinz, Andreas, Wanker, Erich, Priller, Josef, Prigione, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674658/
https://ncbi.nlm.nih.gov/pubmed/33224955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.590540
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