Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay

Excessive ethanol exposure can cause mitochondrial and cellular toxicity. In order to discover potential counteracting interventions, it is essential to develop assays capable of capturing the consequences of ethanol exposure in human neurons, and particularly dopaminergic neurons that are crucial f...

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Publicat a:Front Cell Dev Biol
Autors principals: Zink, Annika, Conrad, Josefin, Telugu, Narasimha Swami, Diecke, Sebastian, Heinz, Andreas, Wanker, Erich, Priller, Josef, Prigione, Alessandro
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674658/
https://ncbi.nlm.nih.gov/pubmed/33224955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.590540
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