Sleep Deprivation Selectively Down-Regulates Astrocytic 5-HT(2B) Receptors and Triggers Depressive-Like Behaviors via Stimulating P2X(7) Receptors in Mice

Chronic loss of sleep damages health and disturbs the quality of life. Long-lasting sleep deprivation (SD) as well as sleep abnormalities are substantial risk factors for major depressive disorder, although the underlying mechanisms are not clear. Here, we showed that chronic SD in mice promotes a g...

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Pubblicato in:Neurosci Bull
Autori principali: Xia, Maosheng, Li, Zexiong, Li, Shuai, Liang, Shanshan, Li, Xiaowei, Chen, Beina, Zhang, Manman, Dong, Chengyi, Verkhratsky, Alexei, Guan, Dawei, Li, Baoman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Singapore 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674526/
https://ncbi.nlm.nih.gov/pubmed/32506374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-020-00524-4
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