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Sleep Deprivation Selectively Down-Regulates Astrocytic 5-HT(2B) Receptors and Triggers Depressive-Like Behaviors via Stimulating P2X(7) Receptors in Mice
Chronic loss of sleep damages health and disturbs the quality of life. Long-lasting sleep deprivation (SD) as well as sleep abnormalities are substantial risk factors for major depressive disorder, although the underlying mechanisms are not clear. Here, we showed that chronic SD in mice promotes a g...
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| Udgivet i: | Neurosci Bull |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Singapore
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7674526/ https://ncbi.nlm.nih.gov/pubmed/32506374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-020-00524-4 |
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