Sleep Deprivation Selectively Down-Regulates Astrocytic 5-HT(2B) Receptors and Triggers Depressive-Like Behaviors via Stimulating P2X(7) Receptors in Mice

Chronic loss of sleep damages health and disturbs the quality of life. Long-lasting sleep deprivation (SD) as well as sleep abnormalities are substantial risk factors for major depressive disorder, although the underlying mechanisms are not clear. Here, we showed that chronic SD in mice promotes a g...

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Publicat a:Neurosci Bull
Autors principals: Xia, Maosheng, Li, Zexiong, Li, Shuai, Liang, Shanshan, Li, Xiaowei, Chen, Beina, Zhang, Manman, Dong, Chengyi, Verkhratsky, Alexei, Guan, Dawei, Li, Baoman
Format: Artigo
Idioma:Inglês
Publicat: Springer Singapore 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674526/
https://ncbi.nlm.nih.gov/pubmed/32506374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-020-00524-4
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