Sleep Deprivation Selectively Down-Regulates Astrocytic 5-HT(2B) Receptors and Triggers Depressive-Like Behaviors via Stimulating P2X(7) Receptors in Mice

Chronic loss of sleep damages health and disturbs the quality of life. Long-lasting sleep deprivation (SD) as well as sleep abnormalities are substantial risk factors for major depressive disorder, although the underlying mechanisms are not clear. Here, we showed that chronic SD in mice promotes a g...

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Détails bibliographiques
Publié dans:Neurosci Bull
Auteurs principaux: Xia, Maosheng, Li, Zexiong, Li, Shuai, Liang, Shanshan, Li, Xiaowei, Chen, Beina, Zhang, Manman, Dong, Chengyi, Verkhratsky, Alexei, Guan, Dawei, Li, Baoman
Format: Artigo
Langue:Inglês
Publié: Springer Singapore 2020
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674526/
https://ncbi.nlm.nih.gov/pubmed/32506374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-020-00524-4
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