Radiation-Induced Damage to Prepubertal Pax7+ Skeletal Muscle Stem Cells Drives Lifelong Deficits in Myofiber Size and Nuclear Number

During prepubertal development, muscle stem cells (satellite cells, SCs) actively contribute to myofiber growth. Because some SCs are active during this time, they may be particularly susceptible to damage. Using a Small Animal Radiation Research Platform (SARRP), we investigated the effects of loca...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Bachman, John F., Blanc, Roméo S., Paris, Nicole D., Kallenbach, Jacob G., Johnston, Carl J., Hernady, Eric, Williams, Jacqueline P., Chakkalakal, Joe V.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674517/
https://ncbi.nlm.nih.gov/pubmed/33241204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101760
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