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Yoda1 and phosphatidylserine exposure in red cells from patients with sickle cell anaemia

Phosphatidylserine (PS) exposure is increased in red cells from sickle cell anaemia (SCA) patients. Externalised PS is prothrombotic and attractive to phagocytes and activated endothelial cells and thus contributes to the anaemic and ischaemic complications of SCA. The mechanism of PS exposure remai...

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Udgivet i:Sci Rep
Main Authors: Wadud, R., Hannemann, A., Rees, D. C., Brewin, J. N., Gibson, J. S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674503/
https://ncbi.nlm.nih.gov/pubmed/33208899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76979-2
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