CBP-mediated Wnt3a/β-catenin signaling promotes cervical oncogenesis initiated by Piwil2

Our previous work demonstrated that Piwil2 reactivated by the human papillomavirus oncoproteins E6 and E7 may reprogram somatic cells into tumor-initiating cells (TICs), which contribute to cervical neoplasia lesions. Maintaining the stemness of TICs is critical for the progression of cervical lesio...

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Bibliographic Details
Published in:Neoplasia
Main Authors: Feng, Dingqing, Yan, Keqin, Liang, Haiyan, Liang, Jing, Wang, Wenhui, Yu, Huan, Zhou, Ying, Zhao, Weidong, Dong, Zhongjun, Ling, Bin
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2020
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674161/
https://ncbi.nlm.nih.gov/pubmed/33190089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2020.10.013
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