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Wnt3a/β-Catenin/CBP Activation in the Progression of Cervical Intraepithelial Neoplasia

Piwil2 reprograms HPV-infected reserve cells in the cervix into tumor-initiated cells (TICs) and upregulates Wnt3a expression sequentially, which leads to cervical intraepithelial neoplasia (CIN) and ultimately squamous cell carcinoma (SCC). However, little is known regarding Wnt signaling in the ma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pathol Oncol Res
Hauptverfasser: Feng, Dingqing, Lin, Jie, Wang, Wenhui, Yan, Keqin, Liang, Haiyan, Liang, Jing, Yu, Huan, Ling, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262210/
https://ncbi.nlm.nih.gov/pubmed/34257574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/pore.2021.609620
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