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Wnt3a/β-Catenin/CBP Activation in the Progression of Cervical Intraepithelial Neoplasia

Piwil2 reprograms HPV-infected reserve cells in the cervix into tumor-initiated cells (TICs) and upregulates Wnt3a expression sequentially, which leads to cervical intraepithelial neoplasia (CIN) and ultimately squamous cell carcinoma (SCC). However, little is known regarding Wnt signaling in the ma...

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Bibliographic Details
Published in:Pathol Oncol Res
Main Authors: Feng, Dingqing, Lin, Jie, Wang, Wenhui, Yan, Keqin, Liang, Haiyan, Liang, Jing, Yu, Huan, Ling, Bin
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262210/
https://ncbi.nlm.nih.gov/pubmed/34257574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/pore.2021.609620
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