Impact of Obesity on Voriconazole Pharmacokinetics among Pediatric Hematopoietic Cell Transplant Recipients

Voriconazole (VCZ) is an antifungal agent with wide inter- and intrapatient pharmacokinetic (PK) variability and narrow therapeutic index. Although obesity was associated with higher VCZ trough concentrations in adults, the impact of obesity had yet to be studied in children. We characterized the PK...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Takahashi, Takuto, Smith, Angela R., Jacobson, Pamala A., Fisher, James, Rubin, Nathan T., Kirstein, Mark N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2020
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674053/
https://ncbi.nlm.nih.gov/pubmed/32988816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00653-20
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