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Highly Variable Plasma Concentrations of Voriconazole in Pediatric Hematopoietic Stem Cell Transplantation Patients

Invasive fungal infections are of great concern in pediatric hematopoietic stem cell transplantation (HSCT) recipients. Voriconazole is usually the drug of first choice for treating or preventing invasive aspergillosis. Optimum trough levels (C(trough)s) are between 1 and 5 mg/liter. It is unclear w...

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Главные авторы: Bartelink, Imke H., Wolfs, Tom, Jonker, Martine, de Waal, Marjolein, Egberts, Toine C. G., Ververs, Tessa T., Boelens, Jaap J., Bierings, Marc
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535953/
https://ncbi.nlm.nih.gov/pubmed/23114771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01540-12
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