Highly Variable Plasma Concentrations of Voriconazole in Pediatric Hematopoietic Stem Cell Transplantation Patients

Invasive fungal infections are of great concern in pediatric hematopoietic stem cell transplantation (HSCT) recipients. Voriconazole is usually the drug of first choice for treating or preventing invasive aspergillosis. Optimum trough levels (C(trough)s) are between 1 and 5 mg/liter. It is unclear w...

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Detalhes bibliográficos
Main Authors: Bartelink, Imke H., Wolfs, Tom, Jonker, Martine, de Waal, Marjolein, Egberts, Toine C. G., Ververs, Tessa T., Boelens, Jaap J., Bierings, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535953/
https://ncbi.nlm.nih.gov/pubmed/23114771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01540-12
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