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A phase I dose finding study of intravenous voriconazole in pediatric patients undergoing hematopoietic cell transplantation
To optimize voriconazole dosing in pediatric hematopoietic cell transplantation (HCT), we conducted a phase I study with a modified 3 + 3 dose-escalation followed by an expansion cohort at the maximum tolerated, minimum efficacious dose (MTD/MED). Patients ≤21 years who required voriconazole for pre...
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| Publicado no: | Bone Marrow Transplant |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7643732/ https://ncbi.nlm.nih.gov/pubmed/31768008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41409-019-0757-0 |
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