Intravenous Voriconazole after Toxic Oral Administration

In a male patient with rhinocerebral invasive aspergillosis, prolonged high-dosage oral administration of voriconazole led to hepatotoxicity combined with a severe cutaneous reaction while intravenous administration in the same patient did not. High concentrations in the portal blood precipitate liv...

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Autori principali: Alffenaar, J. W. C., van Assen, S., de Monchy, J. G. R., Uges, D. R. A., Kosterink, J. G. W., van der Werf, T. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876380/
https://ncbi.nlm.nih.gov/pubmed/20385853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01193-09
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