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Emergence of non-canonical parvalbumin-containing interneurons in hippocampus of a murine model of type I lissencephaly

Type I lissencephaly is a neuronal migration disorder caused by haploinsuffiency of the PAFAH1B1 (mouse: Pafah1b1) gene and is characterized by brain malformation, developmental delays, and epilepsy. Here, we investigate the impact of Pafah1b1 mutation on the cellular migration, morphophysiology, mi...

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Pubblicato in:eLife
Autori principali: Ekins, Tyler G, Mahadevan, Vivek, Zhang, Yajun, D'Amour, James A, Akgül, Gülcan, Petros, Timothy J, McBain, Chris J
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673787/
https://ncbi.nlm.nih.gov/pubmed/33150866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62373
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