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AMPA receptor deletion in developing MGE-derived hippocampal interneurons causes a redistribution of excitatory synapses and attenuates postnatal network oscillatory activity

Inhibitory interneurons derived from the medial ganglionic eminence represent the largest cohort of GABAergic neurons in the hippocampus. In the CA1 hippocampus excitatory synapses onto these cells comprise GluA2-lacking, calcium-permeable AMPARs. Although synaptic transmission is not established un...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Akgül, Gülcan, McBain, Chris J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987165/
https://ncbi.nlm.nih.gov/pubmed/31992779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58068-6
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