Reassessment of the involvement of Snord115 in the serotonin 2c receptor pathway in a genetically relevant mouse model

SNORD115 has been proposed to promote the activity of serotonin (HTR2C) receptor via its ability to base pair with its pre-mRNA and regulate alternative RNA splicing and/or A-to-I RNA editing. Because SNORD115 genes are deleted in most patients with the Prader-Willi syndrome (PWS), diminished HTR2C...

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Detalles Bibliográficos
Publicado en:eLife
Autores principales: Hebras, Jade, Marty, Virginie, Personnaz, Jean, Mercier, Pascale, Krogh, Nicolai, Nielsen, Henrik, Aguirrebengoa, Marion, Seitz, Hervé, Pradere, Jean-Phillipe, Guiard, Bruno P, Cavaille, Jérôme
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673782/
https://ncbi.nlm.nih.gov/pubmed/33016258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60862
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