SNORD116 and SNORD115 change expression of multiple genes and modify each other’s activity

The loss of two gene clusters encoding small nucleolar RNAs, SNORD115 and SNORD116 contributes to Prader-Willi syndrome (PWS), the most common syndromic form of obesity in humans. SNORD115 and SNORD116 are considered to be orphan C/D box snoRNAs (SNORDs) as they do not target rRNAs or snRNAs. SNORD1...

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Bibliographic Details
Published in:	Gene
Main Authors:	Falaleeva, Marina, Surface, Justin, Shen, Manli, de la Grange, Pierre, Stamm, Stefan
Format:	Artigo
Language:	Inglês
Published:	2015
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5586535/ https://ncbi.nlm.nih.gov/pubmed/26220404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2015.07.023
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SNORD116 and SNORD115 change expression of multiple genes and modify each other’s activity

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