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SNORD116 and SNORD115 change expression of multiple genes and modify each other’s activity
The loss of two gene clusters encoding small nucleolar RNAs, SNORD115 and SNORD116 contributes to Prader-Willi syndrome (PWS), the most common syndromic form of obesity in humans. SNORD115 and SNORD116 are considered to be orphan C/D box snoRNAs (SNORDs) as they do not target rRNAs or snRNAs. SNORD1...
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| Publicado no: | Gene |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5586535/ https://ncbi.nlm.nih.gov/pubmed/26220404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2015.07.023 |
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