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Reassessment of the involvement of Snord115 in the serotonin 2c receptor pathway in a genetically relevant mouse model
SNORD115 has been proposed to promote the activity of serotonin (HTR2C) receptor via its ability to base pair with its pre-mRNA and regulate alternative RNA splicing and/or A-to-I RNA editing. Because SNORD115 genes are deleted in most patients with the Prader-Willi syndrome (PWS), diminished HTR2C...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7673782/ https://ncbi.nlm.nih.gov/pubmed/33016258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60862 |
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