A carregar...
Two replication fork remodeling pathways generate nuclease substrates for distinct fork protection factors
Fork reversal is a common response to replication stress, but it generates a DNA end that is susceptible to degradation. Many fork protection factors block degradation, but how they work remains unclear. Here, we find that 53BP1 protects forks from DNA2-mediated degradation in a cell type–specific m...
Na minha lista:
| Publicado no: | Sci Adv |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7673757/ https://ncbi.nlm.nih.gov/pubmed/33188024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc3598 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|