LRRK2 mediates tubulation and vesicle sorting from lysosomes

Genetic variation around the LRRK2 gene affects risk of both familial and sporadic Parkinson’s disease (PD). However, the biological functions of LRRK2 remain incompletely understood. Here, we report that LRRK2 is recruited to lysosomes after exposure of cells to the lysosome membrane–rupturing agen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Adv
Egile Nagusiak: Bonet-Ponce, Luis, Beilina, Alexandra, Williamson, Chad D., Lindberg, Eric, Kluss, Jillian H., Saez-Atienzar, Sara, Landeck, Natalie, Kumaran, Ravindran, Mamais, Adamantios, Bleck, Christopher K. E., Li, Yan, Cookson, Mark R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Association for the Advancement of Science 2020
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673727/
https://ncbi.nlm.nih.gov/pubmed/33177079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb2454
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak