ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL

Understanding the molecular events controlling melanoma progression is of paramount importance for the development of alternative treatment options for this devastating disease. Here we report a mechanism regulated by the oncogenic SOX2-GLI1 transcriptional complex driving melanoma invasion through...

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Udgivet i:Nat Commun
Main Authors: Pietrobono, Silvia, Anichini, Giulia, Sala, Cesare, Manetti, Fabrizio, Almada, Luciana L., Pepe, Sara, Carr, Ryan M., Paradise, Brooke D., Sarkaria, Jann N., Davila, Jaime I., Tofani, Lorenzo, Battisti, Ilaria, Arrigoni, Giorgio, Ying, Li, Zhang, Cheng, Li, Hu, Meves, Alexander, Fernandez-Zapico, Martin E., Stecca, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673140/
https://ncbi.nlm.nih.gov/pubmed/33203881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19575-2
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