Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma

Despite the development of new targeted and immune therapies, the prognosis of metastatic melanoma remains bleak. Therefore, it is critical to better understand the mechanisms controlling advanced melanoma to develop more effective treatment regimens. Hedgehog/GLI (HH/GLI) signaling inhibitors targe...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncogene
Asıl Yazarlar: Pietrobono, Silvia, Gaudio, Eugenio, Gagliardi, Sinforosa, Zitani, Mariapaola, Carrassa, Laura, Migliorini, Francesca, Petricci, Elena, Manetti, Fabrizio, Makukhin, Nikolai, Bond, Adam G., Paradise, Brooke D., Ciulli, Alessio, Fernandez-Zapico, Martin E., Bertoni, Francesco, Stecca, Barbara
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175236/
https://ncbi.nlm.nih.gov/pubmed/33958721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01783-9
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller