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Tolvaptan- and Tolvaptan-Metabolite-Responsive T Cells in Patients with Drug-Induced Liver Injury

[Image: see text] Tolvaptan is an effective drug for the treatment of autosomal dominant polycystic kidney disease, but its use is associated with a significant risk of liver injury in a small number of patients. Herein we describe the presence of tolvaptan- and tolvaptan-metabolite-responsive T cel...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Gibson, Andrew, Hammond, Sean, Jaruthamsophon, Kanoot, Roth, Sharin, Mosedale, Merrie, Naisbitt, Dean J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672698/
https://ncbi.nlm.nih.gov/pubmed/33085478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.0c00328
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