Umbilical Cord-Derived CD362(+) Mesenchymal Stromal Cells Attenuate Polymicrobial Sepsis Induced by Caecal Ligation and Puncture

Mesenchymal stromal cells (MSCs) have a multimodal, immunomodulatory mechanism of action and are now in clinical trials for single organ and systemic sepsis. However, a number of practicalities around source, homogeneity and therapeutic window remain to be determined. Here, we utilised conditioned m...

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Pubblicato in:Int J Mol Sci
Autori principali: Gonzalez, Hector, Keane, Colm, Masterson, Claire H., Horie, Shahd, Elliman, Stephen J., Higgins, Brendan D., Scully, Michael, Laffey, John G., O’Toole, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672591/
https://ncbi.nlm.nih.gov/pubmed/33158246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218270
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