Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung injury potentially via a KGF-dependent mechanism

BACKGROUND: Human mesenchymal stem/stromal cells (hMSCs) represent a promising therapeutic strategy for ventilator-induced lung injury (VILI) and acute respiratory distress syndrome. Translational challenges include restoring hMSC efficacy following cryopreservation, developing effective xenogeneic-...

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Detalhes bibliográficos
Publicado no:Intensive Care Med Exp
Main Authors: Horie, Shahd, Gaynard, Sean, Murphy, Mary, Barry, Frank, Scully, Michael, O’Toole, Daniel, Laffey, John G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002627/
https://ncbi.nlm.nih.gov/pubmed/32025852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-020-0295-5
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