Transcriptomic Analysis of Human Astrocytes In Vitro Reveals Hypoxia-Induced Mitochondrial Dysfunction, Modulation of Metabolism, and Dysregulation of the Immune Response

Hypoxia is a feature of neurodegenerative diseases, and can both directly and indirectly impact on neuronal function through modulation of glial function. Astrocytes play a key role in regulating homeostasis within the central nervous system, and mediate hypoxia-induced changes in response to reduce...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Allen, Scott P., Seehra, Rajpinder Singh, Heath, Paul R., Hall, Benjamin P. C., Bates, Jessica, Garwood, Claire J., Matuszyk, Martyna M., Wharton, Stephen B., Simpson, Julie E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672558/
https://ncbi.nlm.nih.gov/pubmed/33126586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218028
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