Function of a viral genome packaging motor from bacteriophage T4 is insensitive to DNA sequence

Many viruses employ ATP-powered motors during assembly to translocate DNA into procapsid shells. Previous reports raise the question if motor function is modulated by substrate DNA sequence: (i) the phage T4 motor exhibits large translocation rate fluctuations and pauses and slips; (ii) evidence sug...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Mo, Youbin, Keller, Nicholas, delToro, Damian, Ananthaswamy, Neeti, Harvey, Stephen C, Rao, Venigalla B, Smith, Douglas E
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672480/
https://ncbi.nlm.nih.gov/pubmed/33119757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa875
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