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Benchmarking and integrating genome-wide CRISPR off-target detection and prediction

Systematic evaluation of genome-wide Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) off-target profiles is a fundamental step for the successful application of the CRISPR system to clinical therapies. Many experimental techniques and in silico tools have been proposed for detecti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Yan, Jifang, Xue, Dongyu, Chuai, Guohui, Gao, Yuli, Zhang, Gongchen, Liu, Qi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672467/
https://ncbi.nlm.nih.gov/pubmed/33137817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa930
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